{"id":1907,"date":"2026-02-19T16:07:18","date_gmt":"2026-02-19T16:07:18","guid":{"rendered":"https:\/\/crai.es\/?page_id=1907"},"modified":"2026-02-24T18:59:27","modified_gmt":"2026-02-24T18:59:27","slug":"hpcn-pillar","status":"publish","type":"page","link":"https:\/\/crai.es\/en\/hpcn-pillar\/","title":{"rendered":"HPCN Pillar: Human\u2013Plant Coevolution and Neurobiology"},"content":{"rendered":"
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Coevoluci\u00f3n Humano-Planta y Neurobiolog\u00eda<\/mark><\/p>\n\n\n\n

Where evolution connects plants, the brain, and human diversity.<\/mark><\/p>\n<\/div><\/div>\n\n\n\n

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HPCN Pillar: Human\u2013Plant Coevolution and Neurobiology<\/h3>\n\n\n

The HPCN Pillar of CRAI establishes the scientific framework for the study of human\u2013plant coevolution and its impact on neurobiological regulation.\nIt examines how complex phytochemical matrices have historically interacted with human brain architecture, shaping cognitive, emotional, and adaptive dynamics within changing ecological contexts.<\/p>\n\n\n\n

This pillar integrates evolutionary biology, neurobiology, systemic phytochemistry, and computational modelling within a unified methodological architecture aimed at understanding functional configurations rather than isolated components.<\/p>\n<\/div><\/div>\n\n\n\n

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Scientific Axes of the HPCN Pillar<\/h3><\/div>

Our scientific axes focus on the following core dimensions:<\/p><\/div><\/div>\n\n\n\n

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<\/path><\/svg><\/span>Human\u2013plant coevolution as an evolutionary regulatory process<\/span><\/div>\n\n\n\n
<\/path><\/svg><\/span>Interaction between phytochemical matrices and neural networks<\/span><\/div>\n\n\n\n
<\/path><\/svg><\/span>Systemic analysis of the interaction between plant compounds and neural regulation<\/span><\/div>\n\n\n\n
<\/path><\/svg><\/span>Neurobiological variability in complex environmental contexts<\/span><\/div>\n\n\n\n
<\/path><\/svg><\/span>Development of integrative frameworks for systems-based interventions<\/span><\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n
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Articulation into Research Lines<\/h3><\/div>

The HUMAN Pillar unfolds into structural research lines that specifically develop its scientific axes while maintaining methodological coherence within the pillar\u2019s conceptual framework.<\/p><\/div><\/div>\n\n\n\n

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<\/path><\/svg><\/span>Evolutionary bases of human-plant interaction<\/mark><\/strong><\/span><\/div>\n\n\n\n
<\/path><\/svg><\/span>Sustainability and Ecological Modulation of Medicinal Plants<\/mark><\/strong><\/span><\/div>\n\n\n\n
<\/path><\/svg><\/span>Dynamics of Regulation and Resilience in Complex Plant Systems<\/mark><\/strong><\/span><\/div>\n<\/div><\/div>\n\n\n\n
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Lines of research<\/div><\/path><\/svg><\/span><\/a><\/div><\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n
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Methodological approach<\/h3><\/div>

The initiative combines techniques from evolutionary biology, molecular neurobiology, advanced phytochemistry, and computational analysis to study in an integrated way how plant compounds interact with human neural networks. This multidisciplinary approach allows researchers to address neurodiversity from an evolutionary perspective and develop rigorous models for future personalized interventions.<\/p><\/div><\/div>\n\n\n\n

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<\/path><\/svg><\/span>comparative evolutionary biology<\/span><\/div>\n\n\n\n
<\/path><\/svg><\/span>molecular neurobiology<\/span><\/div>\n\n\n\n
<\/path><\/svg><\/span>advanced phytochemistry<\/span><\/div>\n\n\n\n
<\/path><\/svg><\/span>preclinical trials<\/span><\/div>\n\n\n\n
<\/path><\/svg><\/span>metabolomics and transcriptomics<\/span><\/div>\n\n\n\n
<\/path><\/svg><\/span>computational analysis and systems modeling<\/span><\/div>\n<\/div><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n
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Scientific and social relevance<\/h3>\n\n\n\n

This pillar contributes to the consolidation of a scientific framework aimed at understanding human\u2013plant biological modulation within dynamic regulatory contexts, with a forward-looking perspective toward future evidence-based applications.<\/p>\n\n\n\n

Team and collaborations<\/h3>\n\n\n\n

The HPCN Pillar articulates scientific collaboration networks focused on the integrated study of human\u2013plant interaction. Partnerships are fostered with academic institutions, research centers, and technological entities interested in evolutionary, systems-based, and complex phytochemical matrix\u2013oriented approaches.<\/p>\n\n\n\n

Collaboration opportunities<\/h3>\n\n\n\n

The HPCN Pillar promotes scientific cooperation with researchers, academic institutions, and technological entities interested in the evolutionary and systemic study of human\u2013plant interaction.<\/p>\n\n\n\n

Collaborations may be developed at the conceptual, methodological, or experimental level, always within the integrative scientific framework that defines the pillar.<\/p>\n\n\n\n

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Contact<\/a><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

<\/p>","protected":false},"excerpt":{"rendered":"

El Pilar HPCN del CRAI establece el marco cient\u00edfico para el estudio de la coevoluci\u00f3n humano\u2013planta y su impacto en la regulaci\u00f3n neurobiol\u00f3gica.Analiza c\u00f3mo las matrices fitoqu\u00edmicas complejas han interactuado hist\u00f3ricamente con la arquitectura cerebral humana, configurando din\u00e1micas cognitivas, emocionales y adaptativas dentro de contextos ecol\u00f3gicos cambiantes. Este pilar integra biolog\u00eda evolutiva, neurobiolog\u00eda, fitoqu\u00edmica sist\u00e9mica […]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"full-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"enabled","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-1907","page","type-page","status-publish","hentry"],"aioseo_notices":[],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"trp-custom-language-flag":false},"uagb_author_info":{"display_name":"draus@raus-partner.com","author_link":"https:\/\/crai.es\/en\/author\/drausraus-partner-com\/"},"uagb_comment_info":0,"uagb_excerpt":"El Pilar HPCN del CRAI establece el marco cient\u00edfico para el estudio de la coevoluci\u00f3n humano\u2013planta y su impacto en la regulaci\u00f3n neurobiol\u00f3gica.Analiza c\u00f3mo las matrices fitoqu\u00edmicas complejas han interactuado hist\u00f3ricamente con la arquitectura cerebral humana, configurando din\u00e1micas cognitivas, emocionales y adaptativas dentro de contextos ecol\u00f3gicos cambiantes. Este pilar integra biolog\u00eda evolutiva, neurobiolog\u00eda, fitoqu\u00edmica sist\u00e9mica…","_links":{"self":[{"href":"https:\/\/crai.es\/en\/wp-json\/wp\/v2\/pages\/1907","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/crai.es\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/crai.es\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/crai.es\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/crai.es\/en\/wp-json\/wp\/v2\/comments?post=1907"}],"version-history":[{"count":8,"href":"https:\/\/crai.es\/en\/wp-json\/wp\/v2\/pages\/1907\/revisions"}],"predecessor-version":[{"id":2013,"href":"https:\/\/crai.es\/en\/wp-json\/wp\/v2\/pages\/1907\/revisions\/2013"}],"wp:attachment":[{"href":"https:\/\/crai.es\/en\/wp-json\/wp\/v2\/media?parent=1907"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}