{"id":1896,"date":"2026-02-19T16:04:39","date_gmt":"2026-02-19T16:04:39","guid":{"rendered":"https:\/\/crai.es\/?page_id=1896"},"modified":"2026-02-24T19:00:36","modified_gmt":"2026-02-24T19:00:36","slug":"hpcn-lines","status":"publish","type":"page","link":"https:\/\/crai.es\/en\/hpcn-lines\/","title":{"rendered":"Investigaci\u00f3n interdisciplinaria: HPCN"},"content":{"rendered":"
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Research: HPCN Pillar<\/h1><\/div><\/div><\/div><\/div>\n<\/div><\/div>\n\n\n\n
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Research Lines of the HPCN Pillar<\/h2><\/div>\n\n\n\n

CRAI develops integrated scientific frameworks for the study of biological regulation, human\u2013environment coevolution, and neurobiological variability.<\/h3><\/div>

Regulation \u00b7 Coevolution \u00b7 Neurodiversity \u00b7 Phytochemical Matrices<\/strong>

CRAI\u2019s research lines converge in the analysis of interdependent biological systems whose stability and variability emerge from contextual regulatory dynamics.
The centre examines how human profiles are configured and transformed through continuous interaction with ecological and phytochemical matrices, understanding regulation as a dynamic and environment-dependent process.
Research integrates neurobiology, evolutionary ecology, and the analysis of complex plant matrices within a unified methodological architecture aimed at modelling functional configurations rather than isolated entities.
This shared framework enables the interpretation of behavioural and cognitive fluctuations as expressions of dynamic regulatory states, ensuring conceptual coherence and interdisciplinary projection.
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Evolutionary bases of human-plant interaction<\/h4><\/div>

This research line examines the historical-evolutionary interaction between human systems and complex plant matrices.
It analyses how the co-configuration between human neurobiology and phytochemical environments has influenced regulatory, cognitive, and adaptive processes throughout evolution.
Its objective is to develop a conceptual framework that enables the understanding of human\u2013plant modulation within dynamic ecological contexts, with projection toward individualised, systems-based approaches.

Key words:<\/strong> 
Human\u2013plant coevolution; Evolutionary biology; Neurobiological regulation; Complex phytochemistry; Functional ecology; Adaptive systems; Neurodiversity.

This line is developed through specific projects focused on analyzing human\u2013plant modulation within complex evolutionary and regulatory contexts.

Flagship project:<\/strong> <\/p>

NeuroPhytome<\/span><\/path><\/svg><\/a><\/div><\/div><\/div>\n<\/div>\n\n\n\n
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Sustainability and Ecological Modulation of Medicinal Plants<\/h4><\/div>

This research line examines how ecological conditions influence the configuration of complex phytochemical systems in medicinal plants.
It studies the relationship between environmental variability and metabolic dynamics in order to identify the ecological determinants of functional phytochemical profiles.
The approach integrates ecophysiology, sustainability, and systemic regulation to develop production models that are biologically and environmentally coherent.

Key words:<\/strong>
Functional ecology; Mycorrhizal interactions; Biotic and abiotic stress; Plant metabolomics; Environmental variability; Phytochemical systems; Regenerative agriculture.


This line is articulated through projects focused on developing agrobiotechnological strategies aimed at enhancing the stability and functional coherence of phytochemical matrices in medicinal plants.

Flagship project:<\/strong><\/p>

PharmaNtech<\/span><\/path><\/svg><\/a><\/div><\/div><\/div>\n<\/div>\n\n\n\n
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Dynamics of Regulation and Resilience in Complex Plant Systems<\/h4><\/div>

This research line examines the role of medicinal plants within the dynamics of ecosystem resilience and environmental adaptation.
It analyses how ecologically informed management of plant systems can contribute to the functional stability of productive landscapes and restored environments.
The line integrates principles of evolutionary ecology and ecological regulation to develop models linking biodiversity, environmental variability, and long-term biological coherence.

Key words:<\/strong>
Ecosystem resilience; Evolutionary ecology; Functional biodiversity; Ecological restoration; Plant systems; Environmental variability; Agroecology.

This line is developed through projects focused on ecological adaptation and the regeneration of plant systems in response to climate variability and environmental pressure.

Flagship project:<\/strong><\/p>

MountainGreen<\/span><\/path><\/svg><\/a><\/div><\/div><\/div>\n<\/div>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n
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Strategic Projection<\/h3><\/div>

These research lines converge in the development of integrated models aimed at understanding human variability and ecological interactions as expressions of evolutionarily configured regulatory dynamics.\nTheir articulation enables the projection of coherent interpretative frameworks with the potential to generate long-term scientific, environmental, and conceptual applications.<\/p><\/div><\/div>\n<\/div><\/div>\n\n\n\n

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We collaborate with<\/h2><\/div>\n\n\n\n
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\"ReTos-AAA\"<\/figure><\/div>\n\n\n\n
\"CIAGRO1\"<\/figure><\/div>\n\n\n\n
\"IDiBE\"<\/figure><\/div>\n\n\n\n
\"logo_umh\"<\/figure><\/div>\n\n\n\n
\"\"<\/figure><\/div>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n
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Are you interested in collaborating?<\/h3><\/div>

Direct your support to a scientific area you\u2019re passionate about by making a targeted donation to thematic funds. You'll contribute to innovative research and impactful projects that generate knowledge for everyone. Contact us to leave a lasting impact.<\/p>

Collaborate<\/span><\/path><\/svg><\/a><\/div><\/div><\/div>\n\n\n\n
\"estudio_cultivo\"
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Basic research
with sustainable impact<\/h2><\/div><\/figure><\/div>\n<\/div>\n\n\n\n
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Research for a better quality of life<\/h2><\/div>\n\n\n\n

Our researchers strive to expand the boundaries of knowledge in their search for answers, continually exploring new frontiers. While ideas may be limitless, resources are often constrained. Your support can make a meaningful difference. Discover how you can contribute to the CRAI and help advance innovative research through your donation.<\/p><\/div>\n<\/div>\n\n\n\n

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Contact<\/a><\/div>\n<\/div>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"

L\u00edneas de investigaci\u00f3n del Pilar HPCN Colaboramos con Investigaci\u00f3n para una mejor calidad de vida Nuestros investigadores se esfuerzan por expandir los l\u00edmites del conocimiento en su b\u00fasqueda de respuestas, explorando continuamente nuevas fronteras. Aunque sus ideas son infinitas, los recursos a menudo son limitados. Tu apoyo puede marcar la diferencia. Descubre c\u00f3mo puedes contribuir […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"full-width-container","site-content-style":"unboxed","site-sidebar-style":"unboxed","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"enabled","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-1896","page","type-page","status-publish","hentry"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t