When tradition meets science
We are developing a plant extract from Mediterranean species that is traditionally used to treat nervousness and concentration difficulties.
In brief
ADHD and ADHD comorbid with ASD pose significant challenges for those affected and their families. Synthetic medications are often associated with side effects that make long-term use difficult. Our research project offers a promising natural alternative: Based on ethnobotanical and ethnopharmacological studies, we are developing a plant extract traditionally used in children with concentration difficulties.
The project
Our project focuses on the development of an innovative plant extract, primarily derived from Cistus albidus and complemented with other Mediterranean species such as rosemary (Rosmarinus officinalis) and hawthorn (Crataegus monogyna), among others. This unique formula was discovered through an ethnobotanical study, and its efficacy has been confirmed and further explored through ethnopharmacological research.
Preliminary Results
Our results are promising: the extract was described as highly effective in children with typical hyperactivity symptoms. These children showed improved concentration, were less easily distracted, remained calmer, and exhibited reduced irritability and aggressiveness. Analyses suggest that these effects are due to the synergy of compounds such as polyphenols, terpenes, and other plant-based substances with pharmacological properties.
The potential
Our studies indicate that the extract acts on several key aspects related to ADHD and ASD+ADHD: mitochondrial dysfunction, alterations in gut function, neuroimmune dysregulation, and dysregulation of monoaminergic systems.
The next level
To transform this promising discovery into an effective, safe, and accessible alternative, securing the necessary resources is essential. These will enable the initiation of critical clinical phases required to obtain approval from the European Medicines Agency (EMA) and ensure that this natural treatment reaches those who most need it.
